Role of the P2X7 receptor in in vitro and in vivo glioma tumor growth

Human glioblastoma cells are strikingly refractory to ATP-stimulated, P2X7 receptor (P2X7R)-mediated cytotoxicity. To elucidate the mechanistic basis of this feature, we investigated P2X7R-dependent responses in wild type and P2X7R-transfected U138 cells. Mouse GL261 glioma cells were used as an add...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Bergamin, Letícia Scussel, Capece, Marina, Salaro, Erica, Sarti, Alba Clara, Falzoni, Simonetta, Pereira, Mery Stéfani Leivas, De Bastiani, Marco Antônio, Scholl, Juliete Nathali, Battastini, Ana Maria O., Di Virgilio, Francesco
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2019
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690673/
https://ncbi.nlm.nih.gov/pubmed/31448051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27106
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