Involvement of the P2X7-NLRP3 axis in leukemic cell proliferation and death

Lymphocyte growth and differentiation are modulated by extracellular nucleotides and P2 receptors. We previously showed that the P2X7 receptor (P2X7R or P2RX7) is overexpressed in circulating lymphocytes from chronic lymphocytic leukemia (CLL) patients. In the present study we investigated the P2X7R...

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Pubblicato in:Sci Rep
Autori principali: Salaro, Erica, Rambaldi, Alessia, Falzoni, Simonetta, Amoroso, Francesca Saveria, Franceschini, Alessia, Sarti, Alba Clara, Bonora, Massimo, Cavazzini, Francesco, Rigolin, Gian Matteo, Ciccone, Maria, Audrito, Valentina, Deaglio, Silvia, Pelegrin, Pablo, Pinton, Paolo, Cuneo, Antonio, Di Virgilio, Francesco
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879576/
https://ncbi.nlm.nih.gov/pubmed/27221966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26280
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