Non-nucleotide Agonists Triggering P2X7 Receptor Activation and Pore Formation

The P2X7 receptor (P2X7R) is a ligand-gated plasma membrane ion channel belonging to the P2X receptor subfamily activated by extracellular nucleotides. General consensus holds that the physiological (and maybe the only) agonist is ATP. However, scattered evidence generated over the last several year...

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Опубликовано в: :Front Pharmacol
Главные авторы: Di Virgilio, Francesco, Giuliani, Anna L., Vultaggio-Poma, Valentina, Falzoni, Simonetta, Sarti, Alba C.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799242/
https://ncbi.nlm.nih.gov/pubmed/29449813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00039
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