Chronic intrauterine hypoxia alters neurodevelopment in fetal sheep

OBJECTIVE: We tested the hypothesis that chronic fetal hypoxia, at a severity present in many types of congenital heart disease, would lead to abnormal neurodevelopment. METHODS: Eight mid-gestation fetal sheep were cannulated onto a pumpless extracorporeal oxygenator via the umbilical vessels and s...

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Detalhes bibliográficos
Publicado no:J Thorac Cardiovasc Surg
Main Authors: Lawrence, Kendall M., McGovern, Patrick E., Mejaddam, Ali, Rossidis, Avery C., Baumgarten, Heron, Kim, Aimee, Grinspan, Judith B., Licht, Daniel J., Didier, Ryne A., Vossough, Arastoo, Radaelli, Enrico, Rychik, Jack, Song, Limei, Peranteau, William H., Davey, Marcus G., Flake, Alan W., Gaynor, J. William
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690589/
https://ncbi.nlm.nih.gov/pubmed/30745051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2018.12.093
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