Fetal hypoxemia causes abnormal myocardial development in a preterm ex utero fetal ovine model

In utero hypoxia is a major cause of neonatal morbidity and mortality and predisposes to adult cardiovascular disease. No therapies exist to correct fetal hypoxia. In a new ex utero fetal support system, we tested the hypothesis that hypoxemic support of the fetus impairs myocardial development, whe...

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Publicat a:JCI Insight
Autors principals: Lawrence, Kendall M., Hennessy-Strahs, Samson, McGovern, Patrick E., Mejaddam, Ali Y., Rossidis, Avery C., Baumgarten, Heron D., Bansal, Esha, Villeda, Maryann, Han, Jiancheng, Gou, Zhongshan, Zhao, Sheng, Rychik, Jack, Peranteau, William H., Davey, Marcus G., Flake, Alan W., Gaynor, J. William, Bartoli, Carlo R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338387/
https://ncbi.nlm.nih.gov/pubmed/30568044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124338
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