Fetal hypoxemia causes abnormal myocardial development in a preterm ex utero fetal ovine model

In utero hypoxia is a major cause of neonatal morbidity and mortality and predisposes to adult cardiovascular disease. No therapies exist to correct fetal hypoxia. In a new ex utero fetal support system, we tested the hypothesis that hypoxemic support of the fetus impairs myocardial development, whe...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Lawrence, Kendall M., Hennessy-Strahs, Samson, McGovern, Patrick E., Mejaddam, Ali Y., Rossidis, Avery C., Baumgarten, Heron D., Bansal, Esha, Villeda, Maryann, Han, Jiancheng, Gou, Zhongshan, Zhao, Sheng, Rychik, Jack, Peranteau, William H., Davey, Marcus G., Flake, Alan W., Gaynor, J. William, Bartoli, Carlo R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338387/
https://ncbi.nlm.nih.gov/pubmed/30568044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124338
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