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Predicting Protein Dimer Structures Using MELD × MD

It is challenging to predict the docked conformations of two proteins. Current methods are susceptible to errors from treating proteins as rigid bodies and from an inability to compute relative Boltzmann populations of different docked conformations. Here, we show that by using the ClusPro server as...

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Bibliografiske detaljer
Udgivet i:J Chem Theory Comput
Main Authors: Brini, Emiliano, Kozakov, Dima, Dill, Ken A.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690486/
https://ncbi.nlm.nih.gov/pubmed/30908034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.8b01208
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