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The power of multiplexed functional analysis of genetic variants
New technologies have recently enabled saturation mutagenesis and functional analysis of nearly all possible variants of regulatory elements or proteins of interest in single experiments. Here we discuss the past, present, and futureof such multiplexed (functional) assays for variant effects (MAVEs)...
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| Publicado no: | Nat Protoc |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6690347/ https://ncbi.nlm.nih.gov/pubmed/27583640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2016.135 |
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