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Proteopathic Strains and the Heterogeneity of Neurodegenerative Diseases
Most age-related neurodegenerative diseases are associated with the misfolding and aberrant accumulation of specific proteins in the nervous system. The proteins self-assemble and spread by a prion-like process of corruptive molecular templating, whereby abnormally folded proteins induce the misfold...
Guardat en:
| Publicat a: | Annu Rev Genet |
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| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6690197/ https://ncbi.nlm.nih.gov/pubmed/27893962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-genet-120215-034943 |
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