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Adjuvants that stimulate TLR3 or NLPR3 pathways enhance the efficiency of influenza virus-like particle vaccines in aged mice

There is intense interest in the design and use of vaccine strategies against influenza to enhance protective immune responses in the elderly. To address the need for improved influenza vaccines for the aged, two inflammatory adjuvants, Imject® alum (a stimulator of the Nod-like receptor, Nalp3) and...

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書目詳細資料
發表在:Vaccine
Main Authors: Schneider-Ohrum, Kirsten, Giles, Brendan M., Weirback, Heather K., Williams, Brianne L., DeAlmeida, Dilhari R., Ross, Ted M.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690196/
https://ncbi.nlm.nih.gov/pubmed/21963872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.09.051
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