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A Trivalent Virus-Like Particle Vaccine Elicits Protective Immune Responses against Seasonal Influenza Strains in Mice and Ferrets

There is need for improved human influenza vaccines, particularly for older adults who are at greatest risk for severe disease, as well as to address the continuous antigenic drift within circulating human subtypes of influenza virus. We have engineered an influenza virus-like particle (VLP) as a ne...

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Main Authors: Ross, Ted M., Mahmood, Kutub, Crevar, Corey J., Schneider-Ohrum, Kirsten, Heaton, Penny M., Bright, Rick A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698286/
https://ncbi.nlm.nih.gov/pubmed/19554101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006032
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