Safety of intradiscal injection and biocompatibility of polyester amide microspheres in a canine model predisposed to intervertebral disc degeneration

Repair of degenerated intervertebral discs (IVD) might be established via intradiscal delivery of biologic therapies. Polyester amide polymers (PEA) were evaluated for in vitro cytotoxicity and in vivo biocompatibility, and thereafter intradiscal application of PEA microspheres (PEAMs) in a canine m...

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Dades bibliogràfiques
Publicat a:J Biomed Mater Res B Appl Biomater
Autors principals: Willems, Nicole, Mihov, George, Grinwis, Guy C.M., van Dijk, Maarten, Schumann, Detlef, Bos, Clemens, Strijkers, Gustav J., Dhert, Wouter J.A., Meij, Björn P., Creemers, Laura B., Tryfonidou, Marianna A.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2015
Matèries:
Original Research Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690078/
https://ncbi.nlm.nih.gov/pubmed/26687460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.b.33579
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