Biocompatibility and intradiscal application of a thermoreversible celecoxib-loaded poly-N-isopropylacrylamide MgFe-layered double hydroxide hydrogel in a canine model

INTRODUCTION: Chronic low back pain due to intervertebral disc (IVD) degeneration is associated with increased levels of inflammatory mediators. Current medical treatment consists of oral anti-inflammatory drugs to alleviate pain. In this study, the efficacy and safety of a novel thermoreversible po...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Willems, Nicole, Yang, Hsiao-yin, Langelaan, Marloes L. P., Tellegen, Anna R., Grinwis, Guy C. M., Kranenburg, Hendrik-Jan C., Riemers, Frank M., Plomp, Saskia G. M., Craenmehr, Eric G. M., Dhert, Wouter J. A., Papen-Botterhuis, Nicole E., Meij, Björn P., Creemers, Laura B., Tryfonidou, Marianna A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545995/
https://ncbi.nlm.nih.gov/pubmed/26290179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0727-x
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