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Investigation of the allosteric coupling mechanism in a glutamate transporter homolog via unnatural amino acid mutagenesis
Glutamate transporters harness the ionic gradients across cell membranes for the concentrative uptake of glutamate. The sodium-coupled Asp symporter, Glt(Ph) is an archaeal homolog of glutamate transporters and has been extensively used to understand the transport mechanism. A critical aspect of the...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6690018/ https://ncbi.nlm.nih.gov/pubmed/31332002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1907852116 |
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