Patronus is the elusive plant securin, preventing chromosome separation by antagonizing separase

Chromosome distribution at anaphase of mitosis and meiosis is triggered by separase, an evolutionarily conserved protease. Separase must be tightly regulated to prevent the untimely release of chromatid cohesion and disastrous chromosome distribution defects. Securin is the key inhibitor of separase...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Cromer, Laurence, Jolivet, Sylvie, Singh, Dipesh Kumar, Berthier, Floriane, De Winne, Nancy, De Jaeger, Geert, Komaki, Shinichiro, Prusicki, Maria Ada, Schnittger, Arp, Guérois, Raphael, Mercier, Raphael
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690013/
https://ncbi.nlm.nih.gov/pubmed/31324745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906237116
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