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The Structural Complexity and Animal Tissue Distribution of N-Glycolylneuraminic Acid (Neu5Gc)-Terminated Glycans. Implications for Their Immunogenicity in Clinical Xenografting

N-Glycolylneuraminic acid (Neu5Gc)-terminated glycans are present in all animal cells/tissues that are already used in the clinic such as bioprosthetic heart valves (BHV) as well as in those that potentially will be xenografted in the future to overcome end stage cell/organ failure. Humans, as a spe...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Breimer, Michael E., Holgersson, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690001/
https://ncbi.nlm.nih.gov/pubmed/31428616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2019.00057
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