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Characterization of immunogenic Neu5Gc in Bioprosthetic Heart Valves
BACKGROUND: The two common sialic acid (Sia) in mammals are N-Acetylneuraminic acid (Neu5Ac) and its hydroxylated form N-Glycolylneuraminic acid (Neu5Gc). Unlike most mammals, humans cannot synthesize Neu5Gc that is considered foreign and recognized by circulating antibodies. Thus, Neu5Gc is a poten...
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| Published in: | Xenotransplantation |
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| Main Authors: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5036590/ https://ncbi.nlm.nih.gov/pubmed/27610947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12260 |
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