Diaphragm neuromuscular transmission failure in aged rats

In aging Fischer 344 rats, phrenic motor neuron loss, neuromuscular junction abnormalities, and diaphragm muscle (DIAm) sarcopenia are present by 24 mo of age, with larger fast-twitch fatigue-intermediate (type FInt) and fast-twitch fatigable (type FF) motor units particularly vulnerable. We hypothe...

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Bibliografske podrobnosti
izdano v:J Neurophysiol
Main Authors: Fogarty, Matthew J., Gonzalez Porras, Maria A., Mantilla, Carlos B., Sieck, Gary C.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689786/
https://ncbi.nlm.nih.gov/pubmed/31042426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00061.2019
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