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Diaphragm neuromuscular transmission failure in a mouse model of an early-onset neuromotor disorder

The spa transgenic mouse displays spasticity and hypertonia that develops during the early postnatal period, with motor impairments that are remarkably similar to symptoms of human cerebral palsy. Previously, we observed that spa mice have fewer phrenic motor neurons innervating the diaphragm muscle...

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Detalles Bibliográficos
Publicado en:J Appl Physiol (1985)
Autores principales: Fogarty, Matthew J., Brandenburg, Joline E., Sieck, Gary C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988788/
https://ncbi.nlm.nih.gov/pubmed/33382958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00864.2020
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