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Diaphragm neuromuscular transmission failure in a mouse model of an early-onset neuromotor disorder

The spa transgenic mouse displays spasticity and hypertonia that develops during the early postnatal period, with motor impairments that are remarkably similar to symptoms of human cerebral palsy. Previously, we observed that spa mice have fewer phrenic motor neurons innervating the diaphragm muscle...

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Veröffentlicht in:J Appl Physiol (1985)
Hauptverfasser: Fogarty, Matthew J., Brandenburg, Joline E., Sieck, Gary C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988788/
https://ncbi.nlm.nih.gov/pubmed/33382958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00864.2020
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