Diaphragm neuromuscular transmission failure in aged rats

In aging Fischer 344 rats, phrenic motor neuron loss, neuromuscular junction abnormalities, and diaphragm muscle (DIAm) sarcopenia are present by 24 mo of age, with larger fast-twitch fatigue-intermediate (type FInt) and fast-twitch fatigable (type FF) motor units particularly vulnerable. We hypothe...

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Bibliographic Details
Published in:J Neurophysiol
Main Authors: Fogarty, Matthew J., Gonzalez Porras, Maria A., Mantilla, Carlos B., Sieck, Gary C.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689786/
https://ncbi.nlm.nih.gov/pubmed/31042426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00061.2019
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