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A chaperone lid ensures efficient and privileged client transfer during tail-anchored protein targeting
Molecular chaperones play key roles in maintaining cellular proteostasis. In addition to preventing client aggregation, chaperones often relay substrates within a network while preventing off-pathway chaperones from accessing the substrate. Here we show that a conserved lid motif lining the substrat...
Guardat en:
| Publicat a: | Cell Rep |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6689467/ https://ncbi.nlm.nih.gov/pubmed/30605684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.12.035 |
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