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Membrane Recognition and Binding by the Phosphatidylinositol Phosphate Kinase PIP5K1A: A Multiscale Simulation Study
Phosphatidylinositol phosphates (PIPs) are lipid signaling molecules that play key roles in many cellular processes. PIP5K1A kinase catalyzes phosphorylation of PI4P to form PIP(2), which in turn interacts with membrane and membrane-associated proteins. We explore the mechanism of membrane binding b...
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| Published in: | Structure |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cell Press
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6688827/ https://ncbi.nlm.nih.gov/pubmed/31204251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2019.05.004 |
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