A novel animal model of emphysema induced by anti-elastin autoimmunity

Loss of immune tolerance to self-antigens can promote chronic inflammation and disrupt the normal function of multiple organs including the lungs. Degradation of elastin, a highly insoluble protein and a significant component of the lung structural matrix generates pro-inflammatory molecules. Elasti...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Immunol
Prif Awduron: Gu, Bon-Hee, Sprouse, Maran L., Madison, Matthew C., Hong, Monica J., Yuan, Xiaoyi, Tung, Hui-Ying, Landers, Cameron T., Song, Li-Zhen, Corry, David B., Bettini, Maria L., Kheradmand, Farrah
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688643/
https://ncbi.nlm.nih.gov/pubmed/31182478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900113
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