Delivery of Antigen to CD8(+) Dendritic Cells by Fusing Antigen With Formyl Peptide Receptor-Like 1 Inhibitor Protein Induces Antitumor Immunity

A major challenge for vaccine development is targeting antigens to dendritic cells (DCs) in vivo, enabling cross-presentation, and inducing the memory responses. Fcγ receptors (FcγRs) are expressed on many cell types including DCs. Therefore, targeting of antigen to DCs via FcγRs is an attractive st...

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Chiang, Chen-Yi, Wu, Chiao-Chieh, Chen, Yi-Jyun, Liu, Shih-Jen, Leng, Chih-Hsiang, Chen, Hsin-Wei
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688046/
https://ncbi.nlm.nih.gov/pubmed/31428106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01839
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