Delivery of Antigen to CD8(+) Dendritic Cells by Fusing Antigen With Formyl Peptide Receptor-Like 1 Inhibitor Protein Induces Antitumor Immunity

A major challenge for vaccine development is targeting antigens to dendritic cells (DCs) in vivo, enabling cross-presentation, and inducing the memory responses. Fcγ receptors (FcγRs) are expressed on many cell types including DCs. Therefore, targeting of antigen to DCs via FcγRs is an attractive st...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Chiang, Chen-Yi, Wu, Chiao-Chieh, Chen, Yi-Jyun, Liu, Shih-Jen, Leng, Chih-Hsiang, Chen, Hsin-Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688046/
https://ncbi.nlm.nih.gov/pubmed/31428106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01839
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