A Toll-like receptor 2 agonist-fused antigen enhanced antitumor immunity by increasing antigen presentation and the CD8 memory T cells population

The induction of long-lived effector CD8(+) T cells is key to the development of efficient cancer vaccines. In this study, we demonstrated that a Toll-like receptor 2 (TLR2) agonist-fused antigen increased antigen presentation via TLR2 signaling and induced effector memory-like CD8(+) T cells agains...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Wu, Chiao-Chieh, Liu, Shih-Jen, Chen, Hsin-Wei, Shen, Kuan-Yin, Leng, Chih-Hsiang
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058719/
https://ncbi.nlm.nih.gov/pubmed/27127171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9001
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