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The synergistic effects of oxaliplatin and piperlongumine on colorectal cancer are mediated by oxidative stress

Oxaliplatin-based chemotherapy is recommended as the first-line therapeutic regimen for metastatic colorectal cancer. However, long-term and repeated oxaliplatin therapy leads to drug resistance and severe adverse events, which hamper its clinical application. Thus, chemosensitizers are urgently req...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Chen, WeiQian, Lian, WeiShuai, Yuan, YiFeng, Li, MaoQuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687721/
https://ncbi.nlm.nih.gov/pubmed/31395855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1824-6
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