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Primary congenital glaucoma due to paternal uniparental isodisomy of chromosome 2 and CYP1B1 deletion

BACKGROUND: CYP1B1 variants and deletions are the most common cause of primary congenital glaucoma (PCG). METHODS: We investigated an individual with PCG from the Australian and New Zealand Registry of Advanced Glaucoma. We performed sequencing of the CYP1B1 gene, followed by Multiplex Ligation‐depe...

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Détails bibliographiques
Publié dans:Mol Genet Genomic Med
Auteurs principaux: Souzeau, Emmanuelle, Dubowsky, Andrew, Ruddle, Jonathan B., Craig, Jamie E.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687653/
https://ncbi.nlm.nih.gov/pubmed/31251480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.774
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