Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia

Acute myeloid leukemias (AML) are characterized by mutations of tumor suppressor and oncogenes, involving distinct genes in adults and children. While certain mutations have been associated with the increased risk of AML relapse, the genomic landscape of primary chemotherapy resistant AML is not wel...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: McNeer, Nicole A., Philip, John, Geiger, Heather, Ries, Rhonda E., Lavallée, Vincent-Philippe, Walsh, Michael, Shah, Minita, Arora, Kanika, Emde, Anne-Katrin, Robine, Nicolas, Alonzo, Todd A, Kolb, E. Anders, Gamis, Alan S, Smith, Malcolm, Gerhard, Daniela Se, Guidry-Auvil, Jaime, Meshinchi, Soheil, Kentsis, Alex
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687545/
https://ncbi.nlm.nih.gov/pubmed/30760869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0402-3
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