Disease Characteristics and Prognostic Implications of Cell Surface FLT3 Receptor (CD135) Expression in Pediatric Acute Myeloid Leukemia: A Report from the Children’s Oncology Group

PURPOSE: The FLT3 cell-surface receptor tyrosine kinase (CD135) is expressed in a majority of both acute lymphoid leukemia (ALL) and myeloid leukemia (AML). However, the prognostic significance of CD135 expression in AML remains unclear. We therefore evaluated the association between FLT3 surface ex...

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Udgivet i:Clin Cancer Res
Main Authors: Tarlock, Katherine, Alonzo, Todd A., Loken, Michael R., Gerbing, Robert B., Ries, Rhonda E., Aplenc, Richard, Sung, Lillian, Raimondi, Susana C., Hirsch, Betsy A., Kahwash, Samir B., McKenney, Amy, Kolb, E Anders, Gamis, Alan S., Meshinchi, Soheil
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511553/
https://ncbi.nlm.nih.gov/pubmed/28108543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2353
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