Individual liver plasmacytoid dendritic cells are capable of producing IFNα and multiple additional cytokines during chronic HCV infection

Plasmacytoid dendritic cells (pDCs) are “natural” interferon α (IFNα)-producing cells. Despite their importance to antiviral defense, autoimmunity, and ischemic liver graft injury, because DC subsets are rare and heterogeneous, basic questions about liver pDC function and capacity to make cytokines...

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Vydáno v:PLoS Pathog
Hlavní autoři: Doyle, Erin Heather, Rahman, Adeeb, Aloman, Costica, Klepper, Arielle L., El-Shamy, Ahmed, Eng, Francis, Rocha, Chiara, Kim, Sang, Haydel, Brandy, Florman, Sander S., Fiel, M. Isabel, Schiano, Thomas, Branch, Andrea D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687199/
https://ncbi.nlm.nih.gov/pubmed/31356648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007935
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