Individual liver plasmacytoid dendritic cells are capable of producing IFNα and multiple additional cytokines during chronic HCV infection

Plasmacytoid dendritic cells (pDCs) are “natural” interferon α (IFNα)-producing cells. Despite their importance to antiviral defense, autoimmunity, and ischemic liver graft injury, because DC subsets are rare and heterogeneous, basic questions about liver pDC function and capacity to make cytokines...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Doyle, Erin Heather, Rahman, Adeeb, Aloman, Costica, Klepper, Arielle L., El-Shamy, Ahmed, Eng, Francis, Rocha, Chiara, Kim, Sang, Haydel, Brandy, Florman, Sander S., Fiel, M. Isabel, Schiano, Thomas, Branch, Andrea D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687199/
https://ncbi.nlm.nih.gov/pubmed/31356648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007935
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