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Individual liver plasmacytoid dendritic cells are capable of producing IFNα and multiple additional cytokines during chronic HCV infection

Plasmacytoid dendritic cells (pDCs) are “natural” interferon α (IFNα)-producing cells. Despite their importance to antiviral defense, autoimmunity, and ischemic liver graft injury, because DC subsets are rare and heterogeneous, basic questions about liver pDC function and capacity to make cytokines...

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Библиографические подробности
Опубликовано в: :PLoS Pathog
Главные авторы: Doyle, Erin Heather, Rahman, Adeeb, Aloman, Costica, Klepper, Arielle L., El-Shamy, Ahmed, Eng, Francis, Rocha, Chiara, Kim, Sang, Haydel, Brandy, Florman, Sander S., Fiel, M. Isabel, Schiano, Thomas, Branch, Andrea D.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687199/
https://ncbi.nlm.nih.gov/pubmed/31356648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007935
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