Open Chromatin Profiling in Adipose Tissue Marks Genomic Regions with Functional Roles in Cardiometabolic Traits

Identifying the regulatory mechanisms of genome-wide association study (GWAS) loci affecting adipose tissue has been restricted due to limited characterization of adipose transcriptional regulatory elements. We profiled chromatin accessibility in three frozen human subcutaneous adipose tissue needle...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:G3 (Bethesda)
Main Authors: Cannon, Maren E., Currin, Kevin W., Young, Kristin L., Perrin, Hannah J., Vadlamudi, Swarooparani, Safi, Alexias, Song, Lingyun, Wu, Ying, Wabitsch, Martin, Laakso, Markku, Crawford, Gregory E., Mohlke, Karen L.
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2019
Teme:
Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686932/
https://ncbi.nlm.nih.gov/pubmed/31186305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.119.400294
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