Open Chromatin Profiling in Adipose Tissue Marks Genomic Regions with Functional Roles in Cardiometabolic Traits

Identifying the regulatory mechanisms of genome-wide association study (GWAS) loci affecting adipose tissue has been restricted due to limited characterization of adipose transcriptional regulatory elements. We profiled chromatin accessibility in three frozen human subcutaneous adipose tissue needle...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Cannon, Maren E., Currin, Kevin W., Young, Kristin L., Perrin, Hannah J., Vadlamudi, Swarooparani, Safi, Alexias, Song, Lingyun, Wu, Ying, Wabitsch, Martin, Laakso, Markku, Crawford, Gregory E., Mohlke, Karen L.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2019
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686932/
https://ncbi.nlm.nih.gov/pubmed/31186305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.119.400294
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