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CRISPR screens are feasible in TP53 wild‐type cells
A recent study by Haapaniemi et al (2018) reported that intact p53 signaling hampers CRISPR‐based functional genomic screens. Brown et al report good performance of genome‐scale screens in TP53 wild‐type cells and reiterate best practices for CRISPR screening. [Image: see text]
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| Publicado no: | Mol Syst Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6686785/ https://ncbi.nlm.nih.gov/pubmed/31464370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20188679 |
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