Formulation of Biocompatible Targeted ECO/siRNA Nanoparticles with Long-Term Stability for Clinical Translation of RNAi

Nanoparticle based siRNA formulations often suffer from aggregation and loss of function during storage. We in this study report a frozen targeted RGD-polyethylene glycol (PEG)-ECO/siβ3 nanoparticle formulation with a prolonged shelf life and preserved nanoparticle functionality. The targeted RGD-PE...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acid Ther
Main Authors: Ayat, Nadia R., Sun, Zhanhu, Sun, Da, Yin, Michelle, Hall, Ryan C., Vaidya, Amita M., Liu, Xujie, Schilb, Andrew L., Scheidt, Josef H., Lu, Zheng-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686697/
https://ncbi.nlm.nih.gov/pubmed/31140918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2019.0784
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados