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Improving Radiation Response in Glioblastoma Using ECO/siRNA Nanoparticles Targeting DNA Damage Repair

SIMPLE SUMMARY: Glioblastoma (GBM) is the most common form of brain cancer and among the most lethal of human cancers. Radiation therapy is a mainstay in the standard of care for GBM, killing tumor cells by creating DNA damage. Inhibiting DNA damage repair (DDR) proteins enhances radiation therapy b...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Lee, Jennifer A., Ayat, Nadia, Sun, Zhanhu, Tofilon, Philip J., Lu, Zheng-Rong, Camphausen, Kevin
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694254/
https://ncbi.nlm.nih.gov/pubmed/33158243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113260
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