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Evaluation and Reduction of CRISPR Off-Target Cleavage Events

Introduction of CRISPR/Cas9 methods (clustered regularly interspaced short palindromic repeats, CRISPR-associated protein 9) have led to a huge surge in the use of precision genome editing for research applications. Translational medical efforts are likewise rapidly progressing, and Phase I clinical...

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Detalhes bibliográficos
Publicado no:Nucleic Acid Ther
Main Authors: Vakulskas, Christopher A., Behlke, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686686/
https://ncbi.nlm.nih.gov/pubmed/31107154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2019.0790
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