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Design of thiazole orange oligonucleotide probes for detection of DNA and RNA by fluorescence and duplex melting
We have synthesised a range of thiazole orange (TO) functionalised oligonucleotides for nucleic acid detection in which TO is attached to the nucleobase or sugar of thymidine. The properties of duplexes between TO-probes and their DNA and RNA targets strongly depend on the length of the linker betwe...
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| Publicado en: | Org Biomol Chem |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6686645/ https://ncbi.nlm.nih.gov/pubmed/31157811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ob00885c |
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