Loading...
Fluorogenic thiazole orange TOTFO probes stabilise parallel DNA triplexes at pH 7 and above
The instability of DNA triplexes particularly at neutral pH and above severely limits their applications. Here, we demonstrate that the introduction of a thiazole orange (TO) intercalator onto a thymine nucleobase in triplex forming oligonucleotides (TFOs) resolves this problem. The stabilising effe...
Na minha lista:
| Udgivet i: | Chem Sci |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Royal Society of Chemistry
2018
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6182420/ https://ncbi.nlm.nih.gov/pubmed/30393529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc02418a |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|