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Substantial batch effects in TCGA exome sequences undermine pan-cancer analysis of germline variants
BACKGROUND: In recent years, research on cancer predisposition germline variants has emerged as a prominent field. The identity of somatic mutations is based on a reliable mapping of the patient germline variants. In addition, the statistics of germline variants frequencies in healthy individuals an...
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| Veröffentlicht in: | BMC Cancer |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6686424/ https://ncbi.nlm.nih.gov/pubmed/31391007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5994-5 |
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