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Exomic Sequencing to Identify Germline Variants in Familial Melanoma

Germlines are the source of DNA in all cells. A mutation at the germline level is the first step to developing cancer, and the vast majority of cancer is genetic. Melanoma, the leading cause of skin cancer death, is known to be highly heritable and rare. Using a family model, high risk variants rela...

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Detalhes bibliográficos
Main Authors: Landi, Maria Teresa, Shabbir, Hira
Formato: Artigo
Idioma:Inglês
Publicado em: Association of Biomolecular Resource Facilities 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635265/
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