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Exomic Sequencing to Identify Germline Variants in Familial Melanoma
Germlines are the source of DNA in all cells. A mutation at the germline level is the first step to developing cancer, and the vast majority of cancer is genetic. Melanoma, the leading cause of skin cancer death, is known to be highly heritable and rare. Using a family model, high risk variants rela...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Association of Biomolecular Resource Facilities
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3635265/ |
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