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The mechanosensitive Piezo1 channel is required for bone formation
Mechanical load of the skeleton system is essential for the development, growth, and maintenance of bone. However, the molecular mechanism by which mechanical stimuli are converted into osteogenesis and bone formation remains unclear. Here we report that Piezo1, a bona fide mechanotransducer that is...
Gardado en:
| Publicado en: | eLife |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6685704/ https://ncbi.nlm.nih.gov/pubmed/31290742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47454 |
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