The mechanosensitive Piezo1 channel is required for bone formation

Mechanical load of the skeleton system is essential for the development, growth, and maintenance of bone. However, the molecular mechanism by which mechanical stimuli are converted into osteogenesis and bone formation remains unclear. Here we report that Piezo1, a bona fide mechanotransducer that is...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Sun, Weijia, Chi, Shaopeng, Li, Yuheng, Ling, Shukuan, Tan, Yingjun, Xu, Youjia, Jiang, Fan, Li, Jianwei, Liu, Caizhi, Zhong, Guohui, Cao, Dengchao, Jin, Xiaoyan, Zhao, Dingsheng, Gao, Xingcheng, Liu, Zizhong, Xiao, Bailong, Li, Yingxian
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2019
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685704/
https://ncbi.nlm.nih.gov/pubmed/31290742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47454
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