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Vitamin C effects on 5-hydroxymethylcytosine and gene expression in osteoblasts and chondrocytes: Potential involvement of PHD2

Vitamin C (ascorbic acid, AA) is a well-known regulator of bone and cartilage metabolism. However, the mechanisms of AA’s action in these tissues are only partly understood. In this study, we confirmed that AA contributes to bone and cartilage metabolism by showing decreased articular cartilage and...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lindsey, Richard C., Cheng, Shaohong, Mohan, Subburaman
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685624/
https://ncbi.nlm.nih.gov/pubmed/31390373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220653
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