Subsets of ILC3-ILC1-like cells generate a diversity spectrum of ILCs in human mucosal tissues.

Innate lymphoid cells (ILCs) are tissue-resident lymphocytes categorized on the basis of their core regulatory programs and the expression of signature cytokines. Human ILC3s that produce the cytokine IL-22 convert into ILC1-like cells that produce interferon-γ in vitro, but whether this conversion...

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Udgivet i:Nat Immunol
Main Authors: Cella, Marina, Gamini, Ramya, Sécca, Cristiane, Collins, Patrick L., Zhao, Shanrong, Peng, Vincent, Robinette, Michelle L., Schettini, Jorge, Zaitsev, Konstantin, Gordon, William, Bando, Jennifer K., Yomogida, Kentaro, Cortez, Victor, Fronick, Catrina, Fulton, Robert, Lin, Lih-Ling, Gilfillan, Susan, Flavell, Richard A., Shan, Liang, Artyomov, Maxim N., Bowman, Michael, Oltz, Eugene M., Jelinsky, Scott A., Colonna, Marco
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685551/
https://ncbi.nlm.nih.gov/pubmed/31209406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-019-0425-y
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