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Unique and redundant functions of NKp46(+) ILC3s in models of intestinal inflammation
Group 3 ILCs (ILC3s) are innate sources of IL-22 and IL-17 and include lymphoid tissue-inducer (LTi)-like and NKp46(+) subsets. Both depend on RORγt and aryl hydrocarbon receptor, but NKp46(+)ILC3s also require Notch and T-bet for their development and are transcriptionally distinct. The extent to w...
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Publicado no: | J Exp Med |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4612098/ https://ncbi.nlm.nih.gov/pubmed/26458769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151403 |
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