Unique and redundant functions of NKp46(+) ILC3s in models of intestinal inflammation

Group 3 ILCs (ILC3s) are innate sources of IL-22 and IL-17 and include lymphoid tissue-inducer (LTi)-like and NKp46(+) subsets. Both depend on RORγt and aryl hydrocarbon receptor, but NKp46(+)ILC3s also require Notch and T-bet for their development and are transcriptionally distinct. The extent to w...

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Udgivet i:J Exp Med
Main Authors: Song, Christina, Lee, Jacob S., Gilfillan, Susan, Robinette, Michelle L., Newberry, Rodney D., Stappenbeck, Thaddeus S., Mack, Matthias, Cella, Marina, Colonna, Marco
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612098/
https://ncbi.nlm.nih.gov/pubmed/26458769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151403
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